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Early intervention might focus on modulating the initial TGF- response to prevent excessive fibroblast activation and ECM production

Methylphenidate affects task-switching and neural signaling in non-human primates

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More information on these targets and calculations can be found in the DSRIP Measure Specification and Reporting Manual, available on the DSRIP website

When the balance between these reactive species and the body's antioxidant defenses shifts, oxidative stress occurs