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Lipoic acid inhibits leptin secretion and Sp1 activity in adipocytes

High oral doses above 1 g can cause digestive upset, and intravenous doses used in medical settings range from 1025 g per infusion

[DOI] [Google Scholar] 77.OBrien S.M., Fitzgerald P., Scully P., Landers A.M.T., Scott L.V., Dinan T.G

It acts as a humectant, attracting and retaining moisture in the skin

doi: 10.1016/j.annonc.2020.10.596

41 As well as genomic instability, the aging process is characterized by changes to DNA methylation patterns known as epigenetic drift, which ultimately alters gene expression