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Description
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Its core physiological function is to catalyze the methylation of nicotinamide (NAM, a key precursor for NAD+ synthesis) with Sadenosylmethionine (SAM) to produce 1methylnicotinamide (1MNA)
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Microbiota and gut-liver axis: their influences on obesity and obesity-related liver disease
By inhibiting NNMT, 5-Amino-1MQ prevents this NAD drain , allowing cells to maintain higher NAD availability
