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Based on the genotype of MTHFR C677T, the serum level of total homocysteine, vitamin B12, folate, and red blood cell folate, there were significant differences in tHcy concentration between individuals with the TT genotype and those with the CC or CT genotype ( p 12 l mol/L) [73]

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In rodent models, BPC-157 appears quite safe even at high doses, with limited acute toxicity