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ROS The DNA repair mechanisms in mitochondria are immature, which makes the mtDNA susceptible to damage by the oxidative stress caused by ROS

Ultimately, advancing from laboratory studies to well-designed clinical trials will determine whether GSH-responsive nanomedicine can fulfill its potential in precision oncology
Heavy metals (Pb, Cd, As and MeHg) as risk factors for cognitive dysfunction: A general review of metal mixture mechanism in brain

[DOI] [PMC free article] [PubMed] [Google Scholar] 82.Rahmatnezhad L., Moghaddam-Banaem L., Behroozi-Lak T., Shiva A., Rasouli J

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This includes elucidating their absorption, distribution, metabolism, and excretion pathways, and verifying that they do not induce toxicity at intended doses
