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This is also classified as a human carcinogen causing genitourinary disorders like tumors of the lung, prostate, injection site, and other tissues

These cysteine S -conjugates are substrates of cysteine S -conjugate -lyases giving rise to 2-(fluoromethoxy)-1,1,3,3,3-pentafluoropropanethiol and 2-(fluoromethoxy)-1,3,3,3-tetrafluoro-1-propenethiolate, both of which are converted to 2-(fluoromethoxy)-3,3,3-trifluorothionopropanoyl fluoride

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For guidance on managing transitions between tirzepatide and semaglutide during tapering, that comparison covers equivalent doses across both peptides