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Cells use glutathione to manage oxidative stress, support detoxification pathways, and keep the balance between damage and repair inside the cell

Rahman, Faizur

6) scoping review

Concomitant Se deficiency may exaggerate the emergence of the myxedematous form of congenital hypothyroidism

The increase of free iron leads to Fenton reaction (Fe 2+ + H 2 O 2 Fe 3+ + OH + OH ), resulting in ROS accumulation and non-enzymatic lipid peroxidation, which leads to the imbalance of antioxidant system and membrane integrity defect, and finally leads to ferroptosis (Forcina and Dixon 2019) (Fig

doi: 10.1093/brain/aww101
