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Recent evidence indicates that mitophagy is impaired in the hippocampus of AD patients, human AD neurons derived from induced pluripotent stem cells (iPSCs), and AD animal models

The emerging iron-based nanosystems work under such mechanism by promoting Fenton reaction, inhibit GPX4 expression and regulate cell peroxidation exogenously [170, 171]

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M2-like macrophages polarized by Foxp3 Treg-of-B cells ameliorate imiquimod-induced psoriasis

In preclinical and in vitro studies, GHK-Cu has been associated with stimulation of collagen and glycosaminoglycan synthesis, modulation of matrix metalloproteinase activity, and changes in gene expression related to tissue repair