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Acknowledgments The authors gratefully acknowledge the foundational experimental contributions of previous researchers in the field of ferroptosis and periodontitis, whose pioneering work has informed and inspired this review

Plos One 2014

Furthermore, since proteases, such as thrombin, have been reported to support the cleavage of syndecan 1 PG ectodomains, thus facilitating shedding of the GL, the therapeutic use of protease inhibitors should be considered [57]

Many patients experience measurable symptom improvement within a few hours of treatment

Disappointingly, Patient Zeros trough levels remained suboptimal so in January 2017, we moved him to shorter eight-week injection intervals

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