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Eur J Med Chem

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The FDAs accelerated approval was backed by the eNRGy study, which touted a 40% and 33% overall response rate in patients with pancreatic adenocarcinoma and NSCLC, respectively

pH curves for the two DHBA isomers are presented in Figure 3, which clearly illustrates the (de)protonation behavior of the DHBA molecules over the studied pH range, with the dissociation of the carboxylic group at acidic pH and the dissociation of the first hydroxyl group at basic pH clearly visible