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254 NAD + metabolism programs immunity and inflammation NAD + , along with citrate and succinate, is a novel class of metabolites with inflammatory signaling capacity, linking the NAD + metabolism to the programming of immune responses

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Free radicals, characterized by their inherent instability, possess the capacity to inflict cellular damage and contribute significantly to the pathogenesis of various medical conditions, including but not limited to cancer, cardiovascular illnesses, and neurodegenerative disorders (160)

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