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Magnesium lithospermate B attenuates renal injury in 5/6 renal ablation/infarction rats by mitochondrial pathway of apoptosis

4.2.2 Gastrointestinal and hypertensive side effects of curcumin at high doses Although curcumin is best known for its anti-inflammatory and antioxidant properties, at high concentrations it can influence COX enzymes in a way that may lead to gastrointestinal or vascular side effects

In addition, it has the advantage of activating a receptor that is insensitive to the ligand due to mutations in ligand-binding residues (21)

It accelerates the biology that fixes it
