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ROS and chromatin ROS influence the activity of epigenetic modulators, such as histone deacetylases (HDACs) or DNA methyltransferases (DNMTs) with consequences that are evident in the expression of the target genes 38,39
Introduction to free radical biochemistry
doi: 10.1080/13543776.2016.1203419
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These clocks consist of cell-autonomous molecular oscillators that synchronize internal time with environmental lightdark cycles (Takahashi, 2017)
A key feature of HCC is its unique metabolic reprogramming which includes the most extensive alterations in glucose metabolism [11]
