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The application of metabolomics to respiratory diseases and, particularly, to COPD started more than one decade ago and since then the number of scientific publications on the topic has constantly grown

However, attention is drawn to the need for randomized, placebo and controlled clinical trials, with greater sampling to reach more solid conclusions

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Iodine, an essential micronutrient for the synthesis of thyroid hormones, is certainly the main element that links nutrition to the thyroid, but numerous other nutrients and dietary factors are fundamental for the health of the gland and must be taken into consideration in the prevention and treatment of thyroid diseases
