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Overexpression of PCSK9, which binds to LDLR, resulted in a much lower ability of a patient to eliminate LDL-cholesterol (LDL-C) 97
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of the UMDNJ-New Jersey Medical School says about Copper peptides: "The copper-dependent lysyl oxidase (LO) plays a critical role in the biogenesis of connective tissue matrices by cross-linking the extracellular matrix proteins collagen and elastin

[DOI] [PubMed] [Google Scholar] Web Reference 1

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Control group were recruited from healthy persons that matched for age and sex with case group

The answer is two numbers and one formula
