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In human case reports involving serotonergic agents, symptoms progress from agitation and confusion to autonomic instability (tachycardia, blood pressure fluctuations), severe hyperthermia above 40C, and in extreme cases, rhabdomyolysis

Bayraktar, R, Tang, Y, Dragomir, M, Ivan, C, Peng, X, Fabris, L, Zhang, J, Carugo, A, Aneli, S, Liu, J, Chen, MM, Srinivasan, S, Sahnoune, I, Bayraktar, E, Akdemir, KC, Chen, M, Narayanan, P, Huang, W, Ott, LF, Eterovic, AK, Villarreal, OE, Mohammad, MM, Peoples, M, Walsh, D, Hernandez, JA, Morgan, M, Shaw, KR, Davis, JS, Menter, DG, Tam, CS, Yeh, P, Dawson, SJ, Rassenti, LZ, Kipps, TJ, Kunej, T, Estrov, Z, Joosse, SA, Pagani, L, Alix-Panabires, C, Pantel, K, Ferajoli, A, Futreal, A, Wistuba, II, Radovich, M, Kopetz, S , Keating, M, Draetta, G, Mattick, JS, Liang, H, Calin, GA
The reactive thiol (SH) group on its cysteine residue carries its antioxidant activity

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doi: 10.1080/07388551.2023.2286428 122 MonksP
