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Description
Toldo S, Abbate A

Activated IGF-1R is commonly present at focal adhesions, where it can form a ternary complex containing integrin/IGF-1/IGF-1R and protect -integrin from proteasomal or lysosomal degradation, thereby affecting the expression of -integrin and inhibiting cell adhesion to the basement membrane in tumors [50,51]

Specific inhibition of hypoxia inducible factor 1 exaggerates cell injury induced by in vitro ischemia through deteriorating cellular redox environment

L-carnitine (LC) is an endogenous compound synthesized by the human body, and it plays a key role in fatty acid metabolism (Johri et al., 2014)

While disruption of transport of lactate into cancerous cells (i.e., reducing lactate shuttling into cancerous cells) is considered beneficial, upregulation in neuropathological cases shows merit for research

doi:10.1080/00914037.2016.1236339 133
