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That rationale must be backed by non-clinical data confirming the compound behaves as expected and by a thorough safety and toxicology program that identifies potential risks and establishes a safe starting dose for the first human administration and the maximum human exposure that should not be surpassed

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The AOD-9604 rabbit study specifically found that AOD-9604 combined with hyaluronic acid outperformed either treatment alone

Hypothesis/Purpose: The objective of this study was to evaluate the acute non-clinical oral toxicity, gastroprotective activity of monoterpene (-)-Carveol in animal models and the related mechanisms of action

Differences in susceptibility of inbred mice to Bacillus anthracis