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Co-first author Alexandra Beaudry-Richard, MSc, said the findings suggest that low but technically normal B12 could have broader effects than previously recognized

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It has also been observed in vitro that SCs and neurites prefer to travel towards softer stiffness substrates 35,36 , suggesting that materials within the lumen which are stiffer than the surrounding tissues can be inhibitory to nerve growth

This study showed that LNP-based siRNA delivery significantly lowered TTR protein levels and alleviated neuropathy symptoms in patients