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216,217 The detoxification mechanisms also involve the elimination of toxic oxidative metabolites, including peroxides and lipid peroxides, 218,219,220 that can cause cellular damage

This methodology shares similarities with PDT, where light is used instead of ultrasound to activate sensitizers

Ferritin and the response to oxidative stress

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A ge-related macular degeneration (AMD) is the leading cause of blindness among the elderly in Western communities

In contrast, overexpressing SIRT2 enhanced cellular GSH level in 786-O control cells but not in GCLC knockdown 786-O cells (Fig