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Description
University of Minnesota, 2010
With the aggravation of renal I/R injury, sustained activation of Wnt/-catenin signaling promotes the transcription of downstream fibrogenic genes, including SNAI1 , TWIST , PAI1 , and MMP7 , which can induce renal fibrosis and accelerate the progression of AKI to CKD

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Research indicates that acute stress triggers the activation of AgRP neurons, leading to the expression of neuropeptide Y (NPY), which then promotes presynaptic inhibition of GABAergic neurons expressing NPY1R and activates CRH neurons in the paraventricular nucleus (PVN) of the hypothalamus, thereby stimulating the HPA axis and increasing circulating CORT levels

Xuzhu, G
10.1016/j.cofs.2016.02.002 Curr
