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Testicular toxicity: evaluation during drug development

doi: 10.1021/jm061379o

Administration of the aqueous extracts at dosage of 500 mg/kg bw showed hepatoprotective activity against MSG through enhancement of liver functions (MDA improvement, antioxidant activities, histochemical and histological alterations and DNA fragmentation), genotoxicity prevention, and apoptosis inhibition by means of advancing the Bcl-2 mRNA expression

Cell 52 541553 Gong T, Yang Y, Jin T, Jiang W and Zhou R 2018 Orchestration of NLRP3 inflammasome activation by ion fluxes

These neurotrophins play a crucial role in the survival, repair, and regeneration of peripheral nerves, enhancing neuronal health and functional recovery [99,100,101]

these effects were similarly accompanied by an increase in inactivated GSK-3 expression and -catenin activity