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L-carnitine fumarate is generally considered a permissible ingredient within established regulatory frameworks in both the United States and the European Union

Safety Considerations Common Mild Side Effects Nausea and stomach discomfort Diarrhea Fishy smell in breath or sweat (rare) Who Should Consult a Doctor First Individuals with heart diseases People with kidney problems Those with hormonal disorders Pregnant and nursing women Research Consideration: TMAO Some studies raise concerns about high levels of L-Carnitine from supplements possibly leading to increased TMAO (trimethylamine-N-oxide) production, which has been associated with higher risk of heart diseases

L-Carnitine (Levocarnitine) assists in transporting fatty acids into mitochondria where they are converted into energy

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Eur Heart J 1992;13:251-5

Data were tested for normality and variance before statistical testing was applied