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These cytokines may influence central nervous system function through neuroinflammatory pathways and have been implicated in the pathophysiology of fatigue, mood disturbances, and altered pain perception

This review uses comprehensive searches of online databases to compare their clinical presentations, pathophysiologies, and treatments

In addition to optical isomers, astaxanthin displays geometric (E/Z) isomerism due to multiple conjugated double bonds in its polyene chain, with all-trans (all-E) being the major configuration in nature and 9-cis, 13-cis, and 15-cis isomers reported under certain conditions such as heat or light exposure

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[DOI] [PubMed] [Google Scholar] 324.Shingu T., Fujiwara K., Bogler O., Akiyama Y., Moritake K., Shinojima N., Tamada Y., Yokoyama T., Kondo S