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Xihuang pills act on PI3K/Akt/mTOR signaling, a key pathway in blood vessel formation, thus providing a possibility for reversing resistance to chemotherapy 81

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It enhanced the respiratory control ratio RCR and the rate of ADP phosphorylation

Side effects were monitored throughout the treatment course

doi: 10.1007/s12272-018-1069-4

Finally, the review provides recent information on approved products and the clinical trial status of products related to intranasal administration, along with the inclusion of quality-by-designrelated insights