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Acetyl CoA, which is generated from pyruvate, enters the tricarboxylic acid (TCA) cycle and is converted to citric acid, which is essential for synthesis of fatty acids and triglycerides, as well as cholesterol biosynthesis

J Pediatr 97:893900 Willard-Mack CL, Koehler RC, Hirata T, Cork LC, Takahashi H, Traystman RJ, Brusilow SW (1996) Inhibition of glutamine synthetase reduces ammonia-induced astrocyte swelling in rat

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