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Regarding liver and kidney damage in MTX treatment, Bedoui stated that MTX hepatotoxicity may occur due to the depletion of folate reserves and MTX-polyglutamate formation in the liver (Reference Bedoui, Guillot and Slambarom41)

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[DOI] [Google Scholar] 109.Ilesanmi O.I., Adekunle A.E., Omolaiye J.A., Olorode E.M., Ogunkanmi A.L
