melanotan 2 studies 2016 Melanotan 2 – Peptide Foundry

Footnotes Conflicts of interest All authors report no conflict of interest

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Weiss EP, Shah K, Fontana L, Lambert CP, Holloszy JO, Villareal DT

Science 341 , 275278 (2013)

10.1073/pnas.0405596101 Proc

Types of melanin There are two main types of melanin that differently affect skin pigmentation: Eumelanin Gives skin dark brown and black color Main type of melanin in people with dark skin Not water-soluble Provides long-lasting tanning effect Better protection against UV radiation Pheomelanin Red-yellow colored pigment Predominates in people with light skin Water-soluble Causes temporary skin reddening Less effective sun protection The ratio of eumelanin to pheomelanin determines not only skin color but also its ability to tan and susceptibility to sunburn