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In this study we evaluated the applicability of the immortalized human cell line hCMEC/D3 for ABC transporter studies, focusing on the most expressed ABC transporters at the human BBB: P-glycoprotein (PGP, ABCB1), multidrug resistance protein 4 (MRP4, ABCC4) and breast cancer resistance protein (BCRP, ABCG2)

According to the PathCard database, there are about 50 types of microRNAs associated with the development of pathological processes in AD

Wilcoxon t -test) as shown in Fig

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This process ultimately results in damage to the cell membrane and cell death ( In ferroptosis, GPX4 is a critical inhibitor that prevents lipid peroxidation accumulation by reducing lipid peroxides