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Br J Pharmacol

Another study published in the Journal of the American Geriatrics Society found that B12 supplements improved memory and cognitive function in older adults with mild cognitive impairment

This creates two downstream problems: (1) SAM depletion reduces the availability of methyl groups for other critical methylation reactions, including DNA and histone methylation

But who really benefits from these shots

Also, individuals who have undergone certain surgical procedures, including intestinal resection, bypass, or bariatric surgery, which may reduce Vitamin B12 absorption, are also eligible

B12 is a bit of a diva when it comes to lightit's quite sensitive to it