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It decreases the efficacy of the chemotherapy by causing patient discomfort and often resulting in dosage reduction or chemotherapy treatment termination

The evidence for sex as a risk factor for CIPN in the pediatric population is unclear (van de Velde et al., 2017), although some studies report that adult female patients are at greater risk of CIPN following paclitaxel treatment compared to adult males (Greenwald et al., 2019)

Marini, F

SBS8 is found in lung, brain, breast, and prostate cancers and has an unknown etiology

Herder C, Schneitler S, Rathmann W, Haastert B, Schneitler H, Winkler H, et al

When TRPV1 channels become overactive, as they often do in neuropathic conditions, they create hypersensitivity