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DNA-protein cross-links are also possible by initiating chloroethylation at the amino or sulfhydryl group of protein

As observed previously 13 , the putative flavan-3,3,4-triol ( 4 ) was not stable during purification, and confirmatory time-course experiments showed almost complete degradation of the intermediate ( 4 ) within 24 h (Extended Data Fig

Moreover 10 (PNB-0408), a low-molecular weight molecule lacking the N-terminal amino group found in Ang IV analogues enhances cognition and is reported to crosses the blood-brain barrier and subsequently exert its action by interacting with the hepatocyte growth factor/c-Met receptor system

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Needle withdrawal: Withdraw the needle gently