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14987414 [DOI] [PubMed] [Google Scholar] 11.Centers for Disease Control and Prevention, Signs and symptoms of Lyme disease

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Adaptive nanoparticles (TPASIC-PFH@PLGA NPs) are composed of AIEgen TPASIC with ROS generation and photothermal capabilities, perfluorohexane (PFH) as a TME enhancer and photoactivity regulator, and biocompatible polymer poly(lactic-co-glycolic acid) (PLGA) as a biocompatible coating substrate

HLA binding and DC antigen presentation assays can evaluate potential T cell epitopes derived from the mAb, while T cell and PBMC stimulation assays examine whether a mAb can activate immune cells in vitro and ex vivo in terms of cell proliferation and cytokine release