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Reagan-Shaw S, Nihal M, Ahmad N (2008) Dose translation from animal to human studies revisited

Standiford, DA

Compared with those of the lowest tertile, the OR (95 % CI) of NAFLD for the highest tertile of TMAO, betaine, l-carnitine and DMG were 202 (104, 392), 050 (028, 088), 179 (101, 317) and 181 (100, 328), respectively

After the colonization had stabilized (at least 2 weeks after FMT), the hGM received oral carnitine challenge test by gavage administration with d9-carnitine (150 L from a 150-mM stock) dissolved in water

Choline is actively transported across the placenta, leading to fetal plasma choline levels six to seven times higher than maternal blood levels, and amniotic fluid concentrations nearly ten times higher (35)
