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Grigg J, Barber A, Silverman M

MOTS-c Mechanism of Action MOTS-c peptide exerts its biological effects through dual compartmental actions, functioning both within the cytoplasm and, under stress conditions, translocating to the nucleus to directly regulate gene expression

Venter M, Tomas C, Pienaar IS, Strassheim V, Erasmus E, Ng WF, et al

Rice-Evans C, Miller NJ: Total antioxidant status in plasma and body fluids
This allows tissues, such as cardiac muscle, to preserve glucose when fatty acids and/or ketone bodies are being used for energy, because acetyl-CoA synthesis from pyruvate, and therefore from carbohydrates (and some amino acids), is turned off

Expression of octamer-binding transcription factor 4, related to self-renewal functions, is upregulated in hMSCs isolated from human milk (33)
