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Calcific tendonitis of the rotator cuff: From formation to resorption
Interestingly, LTF is also capable of binding directly to LRP1, TGFR2, and IGF-R1, triggering downstream metabolic alterations in osteoblasts (Tian et al., 2023)
These include (i) a low-affinity pathway through CD163 by macrophages (50) and (ii) renal excretion which is accompanied by profound oxidative stress and organ damage (51, 52)
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DNA methylation patterns separate senescence from transformation potential and indicate cancer risk
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