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Description
All these alterations make IGF-1 Long R3 significantly more potent (2-3x) than IGF-1 in studies, because it has a lower affinity to be rendered inactive by IGF binding proteins

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Corso, C
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References Jasmer, K

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NNT activity contributes to 45% of the total NADPH in mitochondrial pool, indicating a significant role of NNT for NADPH pool maintenance, 111 and NADPH obtained by NNT is also used for the reductive carboxylation of -KG to isocitrate mediated by IDH2
