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This immunosuppressive environment is maintained by several cytokines such as IL-6 and TNF-, which activate NF-B/STAT3 signaling, and chemokines such as CCL2 and CXCL12, which bring in monocytes (107, 108)

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In cases of Graves disease, treatment can include antithyroid medications such as methimazole or PTU, which impede thyroid hormone synthesis (Brandfon et al

Some variability within groups could be associated with the lack of control of the study supplement

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Minimum Order Quantities (MOQ) for supplement manufacturing vary significantly based on the manufacturer, formulation complexity, packaging requirements, and other factors