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Another study showed that, consumption of MSG in 600mg/kg and 1.6g/kg body weight on daily basis induced adverse effects on liver and kidney in rat model [41]

Discussion In this study we explored the cellular and subcellular localization of DPEP1 in DRG from normal rats and early (six days) changes elicited after OxPt chemotherapy treatment

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IGF-1 has a molecular structure similar to insulin and possess cross-receptor to activate the downstream pathway, and IGF-1 can also bind IR and specifically activate insulin receptor substrate (IRS), a downstream insulin receptor substrate [24, 25]

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