how long to stay on glp 1 for weight loss maintenance after discontinuing GLP-1 : r/Zepbound How Long for GLP-1 to
Description
JAMA Cardiol 2020

Thats just a drug company strategy for getting a broader indication for these medications rebranding them and marketing them for weight loss. The cost of a GLP-1 medication may be intimidating in that one needs to remain on the drug long-term to maintain its effect for diabetes, weight loss, or perhaps a reduction in depression and anxiety

By activating GLP-1 receptors, they simulate the GLP-1 hormone, which signals fullness to the brain and reduces hunger
The technically accurate terms are "triple agonist" (referring to the three receptors engaged) and "GLP-1/GIP/glucagon receptor agonist" (referring to the specific receptors)

The Bottom Line Should you cover GLP-1 drugs for weight loss

[64] indicated that glucose oxidation plays a key role in GLP-1RA-mediated attenuation of DC