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In individuals with overweight or obesity, treatment with semaglutide was associated with significant reductions in bodyweight, with a mean placebo-subtracted weight loss of 12.4% relative to placebo after 68 weeks reported in the STEP 1 trial

DOI: [DOI] [PubMed] [Google Scholar] 47.Kallmes DF, Comstock BA, Heagerty PJ, et al

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Tjin EP, Groen RW, Vogelzang I, Derksen PW, Klok MD, Meijer HP, van Eeden S, Pals ST, Spaargaren M

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These mutations may arise from internal sources, such as DNA replication errors or inherited genetic variants, as well as external factors like chemical toxins, radiation, and infections