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The additional properties of inhibition of glucagon secretion and inhibition of caloric intake accelerated the development of GLP-1 receptor agonists for usage in type 2 diabetes management [86]

Robert Kushner: That article has been a paradigm shift and there's been so many follow-up articles in response to it with other types of studies that are addressing it

Nausea, bloating, constipation, and sometimes vomiting

doi: 10.1016/j.regpep.2011.12.006

Several additional trends warrant monitoring, though with somewhat lower current velocity

Thyroid tumors: According to FDA labeling, GLP-1 medications carry a boxed warning about thyroid C-cell tumors observed in animal studies