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doi: 10.1096/fj.202002621RR 128 ToriiTMiyamotoYNakataRHigashiYShinmyoYKawasakiHet al

Why Tirzepatide May Work Better Than Single-Action Medications GLP-1-only medications like semaglutide activate one hormone pathway and have demonstrated strong efficacy, with the STEP trials showing up to 18% body weight reduction

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4.4 Therapy-resistance and cancer stemness As a key transcriptional regulator, CEBPB emerges as a pivotal molecular hub driving both therapy resistance and cancer stemness across multiple malignancies
