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In essence, the role of GLP-1 drugs is multifaceted and its burgeoning use could create ripples across various sectors healthcare, pharmaceuticals, food industry, and policy-making, sculpting a future where the management of metabolic disorders is significantly influenced by these agents

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Both included articles showed initial weight loss and a reduction of disease severity following treatment with the GLP-1 agonist, Liraglutide (Table 1)

Experiments by Wong and colleagues [25] showed that GLP1R agonism on IELs inhibited proximal TCR signalling in a PKA-dependent manner [25] and decreased the IEL production of IFN and TNF, thereby abrogating T-cell mediated gut epithelial inflammation and destruction