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Moreover, based on the reduction in major cardiovascular events observed with use of GLP-1R agonists in cardiovascular outcome trials in people with type 2 diabetes [89], large-scale outcome trials in overweight and obesity have been initiated (ClinicalTrials.gov registration no

Curr Med Res Opin 2008;24:275286

In addition, injections avoid many of the drug interactions commonly seen with oral medications, including ones that interfere with absorption in the gut and reduce how well the medicine works

These medicines are powerful and effective, but they are not suitable for everyone and need medical supervision

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