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In the analyses based on PIONEER 4, oral semaglutide 14 mg was associated with improved clinical outcomes and reduced costs versus liraglutide 1.8 mg, and it was therefore considered to be dominant

The RR for achieving the primary outcome in the liraglutide group compared with the placebo was 4.7 (95% CI, 0.375.0

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High triglycerides (above 150 mg/dL) reliably produce small, dense LDL particles

Initiate treatment immediately for acute or severely symptomatic hyponatremia

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