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In summary, the acetyl-L-carnitine group scored better when assessing patient function using the modified Rankin Scale (mRS) and National Institutes of Health Stroke Scale (NIHSS) score, and supplementation caused a significant decline in the serum levels of TNF- , ICAM-1, IL-6, and NSE and a significant increase in the serum level of superoxide dismutase (SOD), TAC, GPx, and total L-carnitine in the subjects with acute ischemic stroke compared to the placebo treatment
However, it is important to note that curcumin has also been identified as a PAINS, exhibiting behaviors such as redox cycling, metal chelation, aggregation, and fluorescence interference that can artificially inflate its apparent bioactivity in vitro (Nelson et al., 2017)
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Differences in Baseline Characteristics and Outcomes in Young Caucasians and African Americans with Acute Myocardial Infarction
Salama A, Elgohary R (2021) L-carnitine and Co Q10 ameliorate potassium dichromate-induced acute brain injury in rats targeting AMPK/AKT/NF-
