list of all glp-1 agonists Indications for GLP-1/GIP RA Summary Sheet and Beyond! GLP-1 Receptor Agonists - Complete

Lancet (2021) 398:14355

Intriguingly these patients experienced a spike in their insulin levels followed by a crash in their blood sugar

These become relevant when GLP-1 class medications are contraindicated, when you want to combine approaches, or when the GLP-1 pathway simply does not produce adequate results for your biology

10.1016/S0140-6736(19)31271-1 Summary Keywords colorectal cancer, gastrointestinal cancer, GLP-1 receptor agonists, liver cancer, meta-analysis, obesity, oncological safety, pancreatic cancer Citation Wali AF, Rangraze I, Khan S, Mufti UB, El-Tanani M and Rizzo M (2026) Reassessing cancer risk with GLP-1 receptor agonists: a comprehensive meta-analysis of gastrointestinal malignancies

Anesthesiology 134(4):526540

In addition to the hormones GIP and glucagon, other hormones such as estrogen, peptide tyrosine tyrosine (PYY), gastrin, xenin, and fibroblast growth factor 21 can be good candidates to pair with GLP-1 and create dual agonists that have anti-diabetic and anti-obesity effects