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Shu-Hong Zhu, who is also the director of the Center for Research and Intervention in Tobacco Control at the University of California, San Diego, told ABC News

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The ordinance will bring a 20 cent-tax hike on all cigars sold in the Windy City, far lower than the 90-cent increase the Mayor originally sought for large cigars

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Tobacco smoke has been shown to inhibit CYP2A6, leading to a decrease or at least a slowdown in nicotine metabolism in smokers compared to non-smokers ( Nicotine not only serves as a substrate for metabolizing enzymes and drug transporters, but also appears to alter their activity