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Laboratory research indicates that cigarette smoking causes toxic cardiovascular effects

doi: 10.1111/j.1469-8137.2006.01787.x 13 FuglsangA

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The risk increases with the amount of cigarettes smoked a day

The result was a dramatic increase in highway crashes, injuries and deaths caused by intoxicated drivers in the 16-20 age group. Data from the National Highway Traffic Safety Administration reveals that in 1988 there were 10,200 drivers age 16-20 years involved in a fatal accident, and 25% of them had a blood alcohol concentration (BAC) of 0.08% or higher (here)

To put some numbers on it: a modern cigarette machine produces 20,000 cigarettes per minute